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Advair Diskus (fluticasone propionate, salmeterol)

How to Use


Shake the device for five seconds before each use.


Hold the diskus device in a horizontal position, place your thumb on the thumb grip and push away from your body until the mouthpiece is exposed. Push the dose lever toward the thumb grip until it clicks. Exhale your breath, then inhale through the mouthpiece. Hold in your breath for around 10 seconds, then exhale slowly.


Rinse your mouth out after each use, do not swallow the water.


Be sure to take this medication at regular intervals and to take it it as directed by your doctor. Do not stop taking it suddenly.


If you miss a dose, you may take the dose as soon as you remember, if it is already almost time for your upcoming dose, take only the upcoming dose and then continue your usual schedule.




Important Information


This is not a rescue inhaler, it is not meant to be used for acute asthma attack episodes. Take it at regular intervals as directed by your healthcare provider.


Notify your healthcare provider if your breathing condition gets worse.


Be sure to notify your doctor if you have any of the following conditions


Milk protein hypersensitivity, bone conditions, diabetes, hypertension, immune system disease, infection, pheochromocytoma, seizures, thyroid disease,  heart conditions.


Side effects that should be immediately reported to your healthcare provider


Allergic reaction(hives, itching, swelling of the face or mouth), chest pain, fever/chills,  heartbeat changes, vision changes, dizziness.



Other Side Effects


Headache, infection, candidiasis, pharyngitis, abdominal pain, arthralgia, constipation, cough, nervousness, stuffy nose, tremors.





12 years and older


Asthma Maintenance


Inhalation Aerosol(Advair HFA 45/21, 115/21, 230/21): 2 inhalations by mouth twice daily (about 12 hours apart).


Dry Powder Inhaler(Advair Diskus 100/50, 250/250, 500/50): 1 inhalation by mouth twice daily (about 12 hours apart).


Chronic Obstructive Pulmonary Disease


Dry Powder Inhaler(Advair Diskus 100/50, 250/50, 500/50): 1 inhalation by mouth twice daily (about 12 hours apart).





Advair is commonly used to treat conditions such as asthma, COPD, and emphysema. Advair contains two different medications which are called  fluticasone and salmeterol. Fluticasone acts as a steroid to decrease inflammatory mediators within the lungs. Salmeterol helps to relax and dilate the cells in your lungs which increases oxygen flow. This is a very effective medication when used as prescribed, and should be taken at regular intervals. It is not meant to be used as a rescue inhaler during sudden asthma attacks.





1. Advair Diskus inhalation powder, fluticasone propionate salmeterol inhalation powder [package insert]. Research Triangle Park, NC: GlaxoSmithKline,; 2010.


2. Advair HFA (fluticasone propionate, salmeterol inhalation aerosol) [package insert]. Research Triangle Park, NC: GlaxoSmithKline; 2014.

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