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Alendronate-Fosamax


How to Use

 

Take this medication by mouth with a glass of water(water only), on an empty stomach right when you wake up in the morning.

 

Do not lie down, eat or drink, or take vitamins or supplements for 30 minutes after taking this medicine.

 

Do not chew or crush the tablet.

 

Take this medication exactly as directed.

 

If you miss a dose, take the dose the morning of the next day, then continue on your normal dose schedule. Do not double up on any dose.

 

 

Important Information

 

Contact your healthcare provider if you get the following symptoms: rash, soar throat, fever, chills, nausea and vomiting, difficulty passing urine or blood in your urine.

 

 

Side effects that you should immediately report to your healthcare provider

 

 

Allergic reaction(hives, itching, swelling of the face or mouth), trouble breathing, pain of the joints, muscles, bone, stomach or chest, vision changes, heartburn, jaw pain, pain or difficulty swallowing, heartbeat changes, any red, blistering, loosening or peeling skin, tarry or black stools.

 

Other Side Effects

 

Diarrhea, constipation, headache, itchy eyes, nausea, vomiting, intestinal gas, taste changes, low calcium and phosphate, flu like symptoms, ulcers of stomach and esophagus.

 

Dose

 

Postmenopausal Osteoporosis

 

10 mg tablet by mouth once daily before breakfast, OR 70 mg tablet by mouth once weekly before breakfast. Often taken with calcium and vitamin D.

 

OR

 

70 mg effervescent tablet to be dissolved in four ounces of water and taken orally once weekly. Often taken with calcium and vitamin D.

 

 

Osteoporosis Prophylaxis in Postmenopausal Women

 

35mg tablet by mouth once weekly before breakfast. Often taken with calcium and vitamin D.

 

OR

 

5mg tablet by mouth once daily. Often taken with calcium and vitamin D.

 

Osteoporosis in Adult Men

 

 10 mg tablet by mouth once daily before breakfast. Often taken with calcium and vitamin D.

 

OR

 

70 mg tablet by mouth once weekly. Often taken with calcium and vitamin D.

 

OR

 

70 mg effervescent tablet to be dissolved in four ounces of water and taken orally once weekly. Often taken with calcium and vitamin D.

 

Osteoporosis from corticosteroids

 

5mg tablet by mouth once daily before breakfast.

 

OR

 

10mg tablet by mouth once daily. (For post menopausal women not taking estrogen therapy).

 

 

Malignant Hypercalcemia

 

Between 5 and 15 mg given intravenously as one infusion over 2-6 hours.

 

 

Paget’s Disease

 

40 mg tablet by mouth once daily for 6 months. Often taken with calcium and vitamin D.

 

 

 

Uses

 

Alendronate is a medication commonly used for bone and calcium conditions. This medication helps your body to use calcium and to create new bone tissue. This is a safe and well tolerated medication when used as prescribed. It is used for conditions such as osteoporosis, Paget’s Disease, thyroid and calcium conditions, osteoporosis prevention, and corticosteroid use.

 

 

 

Resources

 

1. Binosto(TM) oral effervescent tablets, alendronate sodium oral effervescent tablets[package insert]. San Antonio, TX: Mission Pharmacal Company (per FDA); 2012.

 

2. Nussbaum SR, Warrell RP, Rude R Jr, et al: Dose-response study of alendronate sodium for the treatment of cancer-associated hypercalcemia. J Clin Oncol 1993; 11:1618-1623.



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