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Amphetamine/Dextroamphetamine (Adderall)



Amphetamine is known as a sympathomimetic agent which works by increasing the release and transmission of neurotransmitters such as norepinephrine and dopamine in order to achieve its effects. It has been used to treat ADHD, narcolepsy and obesity.


How to Use


Take this medication by mouth with water, do not take more often than directed.


Do not stop taking this medication suddenly after taking it for a long period of time. Minor withdrawal effects can occur. Gradually reduce the dose before stopping.


If you miss a dose, take it as soon as you can. If it is already almost time for your next dose, take only that next dose. Do not double up on any dose.



Important Information


Be sure that your prescribing doctor is aware if you have any of the the following conditions before taking this medication


Anxiety conditions, circulation conditions of toes or fingers, glaucoma, heart conditions, high blood pressure, previous drug or alcohol use problems, previous strokes, kidney or liver disease, mental illness(history of depression, or suicidal thoughts or actions), Tourette’s Syndrome, pregnancy(or planning to become pregnant) or breast-feeding, any conditions involving arteries or blood vessels.



Visit your doctor for regular check ups and monitoring while using this medication.


Do not operate heavy machinery, drive a car, or engage in other activity that required fine motor skills until you are sure of how this medication affects you.


This medicine can decrease your appetite. Talk to your doctor if you are losing weight, or are eating a significantly less amount than you used to. Eating smaller meals more frequently is one way to help this side effect.


This medicine can increase wakefulness, taking it too close to bedtime can decrease your ability to sleep.


Tell your doctor if you notice the medication is losing its effectiveness, or if you need more of the medicine to get the same effect that you used to.



Side effects that should be immediately reported to your healthcare provider


Allergic reaction(hives, itching, rashes, swelling of the face or mouth), trouble breathing, vision changes, persisting chest pain, confusion, changes in heartbeat, hallucinations, mood changes, suicidal thoughts or behaviors, seizures, headaches(severe), dizziness, loss of coordination, uncontrollable movements of the head, neck, arm, mouth or leg, numbness or coolness of the fingers or toes.



Other Side Effects


Abdominal pain, diarrhea, weight loss, appetite loss, nausea, dry mouth, vomiting, dizziness, headache, insomnia, agitation, anxiety, mood changes, urinary tract infections, sneezing, nosebleeds, fever, constipation, fatigue, decreased libido.








5 mg immediate release tablet taken by mouth 1-2 times per day. The dose is typically increased by 5 mg after at least 1 week.




10-20 mg extended release tablets by mouth once daily (taken in morning).


Children 3 to 5 years old


2.5 mg immediate release tablet taken by mouth once a day. The dose is typically increased by 2.5 mg’s after at least 1 week.





1. Evekeo (amphetamine sulfate tablets) [package insert]. Atlanta, GA: Arbor Pharmaceuticals, LLC; 2015.


2. American Academy of Pediatrics subcommittee on attention-deficit/hyperactivity disorder, steering committee on quality improvement and management. ADHD: clinical practice guideline for the diagnosis, evaluation, and treatment of attention-deficit/hyperactivity disorder in children and adolescents. Pediatrics 2011;128(5):1007-1022.

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