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Celebrex(Celecoxib)


Uses

 

Celebrex(Celecoxib) is a cyclooxygenase(COX) inhibitor, similar to other drugs of the NSAID class such as ibuprofen and naproxen. Celebrex is unique because it specifically blocks the COX -2 enzyme stronger than the other subtypes of the enzyme. By blocking this enzyme it decreases the production of prostaglandins and thromboxanes, decreasing inflammation and pain within the human body.

 

How to Use

 

Take this medication by mouth with water.

 

Take it exactly as directed and at regular intervals, do not take more than directed.

 

If you take 400 mg or more at once, or if it upsets your stomach,  take it with food.

 

Do not lie down for 10 minutes after taking this medication.

 

If you miss a dose, take it as soon as you can. If it is already almost time for your next dose, take only that next dose. Do not double up on any dose.

 

 

Important Information

 

If your pain dose not improve, do not self treat with other medications, instead, contact your doctor.

 

Using this medicine for a long period of time may increase your chances of getting a stroke or heart attack. If you take aspirin to minimize chances of heart attacks or strokes, or  if you have heart disease, discuss this with your doctor.

 

Do not take medications such as ibuprofen or naproxen while taking this medication. Consult with your doctor before taking another medication to treat pain. This may increase your risk of developing stomach upset or ulcers.

 

This medication can cause stomach ulcers and stomach bleeding, this can happen without warning symptoms and can cause death.

 

 

Be sure that your prescribing doctor is aware if you have any of the the following conditions before taking this medication

 

Asthma, coronary artery bypass graft within the past 2 weeks, consuming more than 3 alcoholic drinks per day, high blood pressure, kidney disease, liver disease, stomach ulcers or other stomach conditions, allergic reaction history, pregnancy or breastfeeding.

 

 

Side effects that should be immediately reported to your healthcare provider

 

Allergic reactions(hives, itching, swelling of the face or mouth), trouble breathing, black or bloody stools, vision changes, chest pain, nausea or vomiting, trouble walking or lack of balance, any red, blistering, loosening or peeling skin, swelling, weight gain, fatigue, yellowish skin or eyes.

 

 

Other Side Effects

 

Constipation, heartburn, gas, upset stomach, dizziness.

 

 

Adult Dose

 

Acute Gout Attack

 

800 mg taken right away, then 400 mg every 12 hours for 7 days.

 

 

Rheumatoid Arthritis

 

100-200 mg by mouth twice per day.

 

 

Headache, Bone Pain, Dental Pain, Dysmenorrhea, and Surgical Pain

 

400 mg by mouth on the first day, followed by another 200 mg if needed. Then, 200 mg by mouth twice per day on the following days.

 

 

Sources

 

1. Celebrex® oral capsules, celecoxib oral capsules[package insert]. G.D. New York, NY: Searle LLC; 2011.

 

2. Chan CC, Boyce S, Brideau C, et al. Rofecoxib Vioxx, MK-0966; [4-(4'-methylsulfonylphenyl)-3-phenyl-2-(5H)-furone]: a potent and orally active cyclooxygenase-2 inhibitor. Pharmacological and biochemical profiles. J Clin Pharmacol Exp Ther 1999;290:551-560.


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