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Lisinopril is an ACEI (Angiotension Converting Enzyme Inhibitor). It decreases the body’s production of angiotension 2, a molecule which causes vasoconstriction and increases blood pressure. It is used to treat conditions such as heart failure, high blood pressure and heart attacks.


How to Use:


Take this medication by mouth with water, it can be taken with or without food.


Take it exactly as directed, do not take it more than directed.


Consult with your doctor before discontinuing this medication or if bothersome side effects occur.


If you miss a dose, take it as soon as you can. If it is already almost time for your next dose, take only that next dose. Do not double up on any dose.



Important Information


Contact your doctor if you notice a persistent fast heartbeat.


Check your blood pressure and meet with your doctor regularly while on this medication.


Stand and sit slowly when first starting this medication to avoid dizziness.


Do not operate heavy machinery, drive a car, or engage in other activity that requires fine motor skills until you are sure of how this medication affects you.


Avoid alcohol consumption, alcohol can increase chance of dizziness or drowsiness.


Notify your doctor if you get an attack of nausea and vomiting, diarrhea, or excessive sweating. Excessive body fluid loss while taking this medication can have adverse effects.


Do not self treat for coughs and colds using over the counter medications without consulting with your doctor first, these medications can affect your blood pressure.



Be sure that your prescribing doctor is aware if you have any of the the following conditions before taking this medication


Diabetes, all heart and circulatory conditions, low blood pressure, immune system disorders, allergic reaction history, low blood pressure, swelling of the lips, tongue, or face with difficulty breathing or tightening of throat,  pregnancy, breastfeeding, trying to become pregnant.



Side effects that should be immediately reported to your healthcare provider


Allergic reaction(hives, itching, swelling of the face or mouth), trouble breathing, abdominal pain, darkened urine, fainting or lightheadedness, fever, soar throat, yellowing of skin or eyes, persistent weakness, any red, peeling or loose skin.


Other Side Effects


Cough, libido changes, fatigue, increased sun sensitivity, headache, taste changes.



Adult Dose





10 mg by mouth once daily as a starting dose. The dose can be increased over time to 20-40 mg per day. If this medication is taken with a diuretic, then the starting dose is typically 5mg per day.



Kidney Disease


5-20 mg by mouth once daily.





1. Zestril (R) oral tablets, lisinopril oral tablets. Wilmington, DE:  AstraZeneca Pharmaceuticals LP (per FDA);  2014.


2. Shiigai T & Shichiri M: Late escape from the antiproteinuric effect of ace inhibitors in nondiabetic renal disease. Am J Kidney Dis 2001; 37(3):477-483

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