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Pantoprazole (Protonix)


Uses

 

Pantoprazole (Protonix) is a proton pump inhibitor which works by absorbing into the blood stream and eventually acting on the K+/H+ ATPase pump which secretes stomach acid from the stomach’s parietal cells. It is effective in the treatment of heartburn, ulcers, and other secretory conditions.

 

 

How to Use

 

Take this medication by mouth with water, it can be taken with or without food.

 

Do not crush break or chew the tablets.

 

Take it exactly as directed, do not take it more than directed.

 

If you miss a dose, take it as soon as you can. If it is already almost time for your next dose, take only that next dose. Do not double up on any dose.

 

 

Important Information

 

It may take a few days before this medicine begins to work. Talk to your doctor if your symptoms are not improving or are getting worse.

 

Your doctor may require blood work while taking this medicine.

 

 

Be sure that your prescribing doctor is aware if you have any of the the following conditions before taking this medication

 

Low magnesium levels, liver disease, pregnancy, allergic reaction history, breastfeeding, trying to become pregnant.

 

 

Side effects that should be immediately reported to your healthcare provider

 

Allergic reactions (hives, rashes, itching, swelling of the face or mouth), trouble breathing, bone pain, muscle pain, muscle spasms, joint pain, dark colored urine, heartbeat changes(fast heartbeat), seizures, tremors, yellowing of the skin or eyes, excessive fatigue, fever, sore throat, lightheadedness or fainting, chest pain, unusual bleeding or bruising.

 

 

Other Side Effects

 

Diarrhea, constipation, headache, nausea, dry mouth.

 

 

Adult Dose

 

Duodenal Ulcer Disease

 

40-80 mg by mouth once daily for  4-8 weeks.

 

 

Erosive Esophagitis

 

40 mg by mouth once daily for up to 8 weeks.

 

 

Mild Gastroesophageal Reflux Disease

 

20 mg by mouth once daily for 4 weeks.

 

 

Zollinger Ellison Syndrome (or other hypersecratory conditions)

 

40 mg by mouth twice daily.

 

 

Sources

 

1. Protonix delayed-release oral tablets, suspension, pantoprazole sodium delayed-release oral tablets, suspension[package insert]. Philadelphia, PA: Wyeth Pharmaceuticals Inc; 2009.

 

2. Protonix R) IV injection, pantoprazole sodium IV injection[package insert]. Philadelphia, PA: Wyeth Pharmaceuticals, Inc; 2007.

 

3. Protonix (pantoprazole) [package insert]. Philadelphia, PA: Wyeth Pharmaceuticals, Inc.; 2014 Dec.


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