General Information
Symptoms
Diagnosis
Treatment
Nutrition
Lactose is a sugar found in milk and milk products. The small intestine-the organ where most food digestion and nutrient absorption take place-produces an enzyme called lactase. Lactase breaks down lactose into two simpler forms of sugar: glucose and galactose. The body then absorbs these simpler sugars into the bloodstream.
Lactose intolerance is a condition in which people have digestive symptoms-such as bloating, diarrhea, and gas-after eating or drinking milk or milk products.
Lactase deficiency and lactose malabsorption may lead to lactose intolerance:
People have lactose intolerance when lactase deficiency and lactose malabsorption cause digestive symptoms. Most people with lactose intolerance can eat or drink some amount of lactose without having digestive symptoms. Individuals vary in the amount of lactose they can tolerate.
People sometimes confuse lactose intolerance with a milk allergy. While lactose intolerance is a digestive system disorder, a milk allergy is a reaction by the body's immune system to one or more milk proteins. An allergic reaction to milk can be life threatening even if the person eats or drinks only a small amount of milk or milk product. A milk allergy most commonly occurs in the first year of life, while lactose intolerance occurs more often during adolescence or adulthood.1,2
Four types of lactase deficiency may lead to lactose intolerance:
In the United States, some ethnic and racial populations are more likely to have lactose intolerance than others, including African Americans, Hispanics/Latinos, American Indians, and Asian Americans. The condition is least common among Americans of European descent.2
Common symptoms of lactose intolerance include
Symptoms occur 30 minutes to 2 hours after consuming milk or milk products. Symptoms range from mild to severe based on the amount of lactose the person ate or drank and the amount a person can tolerate.
In addition to causing unpleasant symptoms, lactose intolerance may affect people's health if it keeps them from consuming enough essential nutrients, such as calcium and vitamin D. People with lactose intolerance may not get enough calcium if they do not eat calcium-rich foods or do not take a dietary supplement that contains calcium. Milk and milk products are major sources of calcium and other nutrients in the diet. Calcium is essential at all ages for the growth and maintenance of bones. A shortage of calcium intake in children and adults may lead to bones that are less dense and can easily fracture later in life, a condition called osteoporosis.
A health care provider makes a diagnosis of lactose intolerance based on
Medical, family, and diet history. A health care provider will take a medical, family, and diet history to help diagnose lactose intolerance. During this discussion, the health care provider will review a patient's symptoms. However, basing a diagnosis on symptoms alone may be misleading because digestive symptoms can occur for many reasons other than lactose intolerance. For example, other conditions such as irritable bowel syndrome, celiac disease, inflammatory bowel disease, or small bowel bacterial overgrowth can cause digestive symptoms.
Physical exam. A physical exam may help diagnose lactose intolerance or rule out other conditions that cause digestive symptoms. During a physical exam, a health care provider usually
A health care provider may recommend eliminating all milk and milk products from a person's diet for a short time to see if the symptoms resolve. Symptoms that go away when a person eliminates lactose from his or her diet may confirm the diagnosis of lactose intolerance.
Medical tests. A health care provider may order special tests to provide more information. Health care providers commonly use two tests to measure how well a person digests lactose:
Most people with lactose intolerance can tolerate some amount of lactose in their diet and do not need to avoid milk or milk products completely. Avoiding milk and milk products altogether may cause people to take in less calcium and vitamin D than they need. See the "Calcium and Vitamin D" section.
Individuals vary in the amount of lactose they can tolerate. A variety of factors-including how much lactase the small intestine produces-can affect how much lactose an individual can tolerate. For example, one person may have severe symptoms after drinking a small amount of milk, while another person can drink a large amount without having symptoms. Other people can easily eat yogurt and hard cheeses such as cheddar and Swiss, while they are not able to eat or drink other milk products without having digestive symptoms.
Research suggests that adults and adolescents with lactose malabsorption could eat or drink at least 12 grams of lactose in one sitting without symptoms or with only minor symptoms. This amount is the amount of lactose in 1 cup of milk. People with lactose malabsorption may be able to eat or drink more lactose if they eat it or drink it with meals or in small amounts throughout the day.2
Many people can manage the symptoms of lactose intolerance by changing their diet. Some people may only need to limit the amount of lactose they eat or drink. Others may need to avoid lactose altogether. Using lactase products can help some people manage their symptoms.
For people with secondary lactase deficiency, treating the underlying cause improves lactose tolerance. In infants with developmental lactase deficiency, the ability to digest lactose improves as the infants mature. People with primary and congenital lactase deficiency cannot change their body's ability to produce lactase.
People may find it helpful to talk with a health care provider or a registered dietitian about a dietary plan. A dietary plan can help people manage the symptoms of lactose intolerance and make sure they get enough nutrients. Parents, caretakers, childcare providers, and others who serve food to children with lactose intolerance should follow the dietary plan recommended by the child's health care provider or registered dietitian.
Milk and milk products. Gradually introducing small amounts of milk or milk products may help some people adapt to them with fewer symptoms. Often, people can better tolerate milk or milk products by having them with meals, such as having milk with cereal or having cheese with crackers. People with lactose intolerance are generally more likely to tolerate hard cheeses, such as cheddar or Swiss, than a glass of milk. A 1.5-ounce serving of low-fat hard cheese has less than 1 gram of lactose, while a 1-cup serving of low-fat milk has about 11 to 13 grams of lactose.2
However, people with lactose intolerance are also more likely to tolerate yogurt than milk, even though yogurt and milk have similar amounts of lactose.2
Lactose-free and lactose-reduced milk and milk products. Lactose-free and lactose-reduced milk and milk products are available at most supermarkets and are identical nutritionally to regular milk and milk products. Manufacturers treat lactose-free milk with the lactase enzyme. This enzyme breaks down the lactose in the milk. Lactose-free milk remains fresh for about the same length of time or, if it is ultra-pasteurized, longer than regular milk. Lactose-free milk may have a slightly sweeter taste than regular milk.
Lactase products. People can use lactase tablets and drops when they eat or drink milk products. The lactase enzyme digests the lactose in the food and therefore reduces the chances of developing digestive symptoms. People should check with a health care provider before using these products because some groups, such as young children and pregnant and breastfeeding women, may not be able to use them.
Ensuring that children and adults with lactose intolerance get enough calcium is important, especially if their intake of milk and milk products is limited. The amount of calcium a person needs to maintain good health varies by age. Table 1 illustrates recommendations for calcium intake.
Table 1. Recommended Dietary Allowance of calcium by age group | |
---|---|
Age Group | Recommended Dietary Allowance (mg/day) |
1-3 years | 700 mg |
4-8 years | 1,000 mg |
9-18 years | 1,300 mg |
19-50 years | 1,000 mg |
51-70 years, males | 1,000 mg |
51-70 years, females | 1,200 mg |
70+ years | 1,200 mg |
14-18 years, pregnant/breastfeeding | 1,300 mg |
19-50 years, pregnant/breastfeeding | 1,000 mg |
A U.S. Recommended Dietary Allowance for calcium has not been determined for infants. However, researchers suggest 200 mg of calcium per day for infants age 0 to 6 months and 260 mg for infants age 6 to 12 months.3
Many foods can provide calcium and other nutrients the body needs. Nonmilk products high in calcium include fish with soft bones, such as canned salmon and sardines, and dark green vegetables, such as spinach. Manufacturers may also add calcium to fortified breakfast cereals, fruit juices, and soy beverage-also called soy milk. Many fortified foods are also excellent sources of vitamin D and other essential nutrients, in addition to calcium.
Table 2 lists foods that are good sources of dietary calcium.
Table 2. Calcium content in common foods | |
---|---|
Nonmilk Products | Calcium Content |
sardines, with bone, 3.75 oz. | 351 mg |
rhubarb, frozen, cooked, 1 cup | 348 mg |
soy milk, original and vanilla, with added calcium and vitamins A and D | 299 mg |
spinach, frozen, cooked, 1 cup | 291 mg |
salmon, canned, with bone, 3 oz. | 181 mg |
pinto beans, cooked, 1 cup | 79 mg |
broccoli, cooked, 1 cup | 62 mg |
soy milk, original and vanilla, unfortified, 1 cup | 61 mg |
orange, 1 medium | 52 mg |
lettuce, green leaf, 1 cup | 13 mg |
tuna, white, canned, 3 oz. | 12 mg |
Milk and Milk Products | |
yogurt, plain, skim milk, 8 oz. | 452 mg |
milk, reduced fat, with added vitamins A and D, 1 cup | 293 mg |
Swiss cheese, 1 oz. | 224 mg |
cottage cheese, low fat, 1 cup | 206 mg |
ice cream, vanilla, 1/2 cup | 84 mg |
Source: Adapted from U.S. Department of Agriculture, Agricultural Research Service. 2013. USDA national nutrient database for standard reference, release 26.
Vitamin D helps the body absorb and use calcium. Some people with lactose intolerance may not get enough vitamin D. Foods such as salmon, tuna, eggs, and liver naturally contain vitamin D. Most milk sold in the United States is fortified with vitamin D, and vitamin D is added to some nonmilk beverages, yogurts, and breakfast cereals. People's bodies also make vitamin D when the skin is exposed to sunlight.
People may find it helpful to talk with a health care provider or a registered dietitian to determine if their diet provides adequate nutrients-including calcium and vitamin D. To help ensure coordinated and safe care, people should discuss their use of complementary and alternative medical practices, including their use of dietary supplements, with their health care provider. Read more at www.ods.od.nih.gov and www.nccam.nih.gov .
Lactose is present in many food products and in some medications.
Lactose is in all milk and milk products. Manufacturers also often add milk and milk products to boxed, canned, frozen, packaged, and prepared foods. People who have digestive symptoms after consuming a small quantity of lactose should be aware of the many food products that may contain even small amounts of lactose, such as
People can check the ingredients on food labels to find possible sources of lactose in food products. If a food label includes any of the following words, the product contains lactose:
Some medications also contain lactose, including prescription medications such as birth control pills and over-the-counter medications such as products to treat stomach acid and gas. These medications most often cause symptoms in people with severe lactose intolerance. People with lactose intolerance who take medications that contain lactose should speak with their health care provider about other options.
[1] Boyce JA, Assa'ad A, Burks AW, et al. Guidelines for the diagnosis and management of food allergy in the United States: report of the NIAID-sponsored expert panel. Journal of Allergy and Clinical Immunology. 2010;126(6 suppl.):S1-S58.
[2] Suchy FJ, Brannon PM, Carpenter TO, et al. National Institutes of Health Consensus Development Conference: lactose intolerance and health. Annals of Internal Medicine. 2010;152(12):792-796.
[3] Institute of Medicine, National Academy of Sciences. Dietary Reference Intakes for Calcium and Vitamin D. 2010. Report.
-NIH