Echinacea
Background
There
are nine known species of echinacea, all of which are native to North
America. They were used by Native Americans of the Great Plains region
as traditional medicines.
Echinacea is used as a dietary
supplement for the common cold and other infections, based on the idea
that it might stimulate the immune system to more effectively fight
infection. Echinacea preparations have been used topically (applied to
the skin) for wounds and skin problems.
The roots and
above-ground parts of the echinacea plant are used fresh or dried to
make teas, squeezed (expressed) juice, extracts, capsules and tablets,
and preparations for external use. Several species of echinacea, most
commonly
Echinacea purpurea or
Echinacea angustifolia,
may be included in dietary supplements.
How Much Do We Know?
Many
studies have been done on echinacea and the common cold. Much less
research has been done on the use of echinacea for other
health purposes.
What Have We Learned?
Taking echinacea after you catch a cold has not been shown to shorten
the time that you’ll be sick.
Taking
echinacea while you’re well may slightly reduce your chances of
catching a cold. However, the evidence on this point isn’t completely
certain. Currently, the National Center for Complementary and
Integrative Health (NCCIH) is funding research to identify the active
constituents in echinacea and to study the effects on the human immune
system of substances in bacteria that live within
echinacea plants.
What Do We Know About Safety?
There
are many different echinacea products. They may contain different
species of plants or different parts of the plant, be manufactured in
different ways, and have other ingredients in addition to echinacea.
Most of these products have not been tested in people.
For most people, short-term oral (by mouth) use of echinacea is
probably safe; the safety of long-term use is uncertain.
The most common side effects of echinacea are digestive tract symptoms,
such as nausea or stomach pain.
Some
people have allergic reactions to echinacea, which may be severe. Some
children participating in a clinical trial of echinacea developed
rashes, which may have been caused by an allergic reaction. People with
atopy (a genetic tendency toward allergic reactions) may be more likely
to have an allergic reaction when taking echinacea.
Current evidence indicates that the risk of interactions between
echinacea supplements and most medications is low.
Keep in Mind
Tell
all your health care providers about any complementary or integrative
health approaches you use. Give them a full picture of what you do to
manage your health. This will help ensure coordinated and
safe care.
Key References
- Barrett
B, Brown R, Rakel D, et al. Echinacea
for treating the common cold: a randomized trial. Annals of Internal Medicine. 2010;153(12):769-777.
- Bauer
R, Woelkart K. Echinacea species. In: Coates PM, Betz JM, Blackman MR,
et al., eds. Encyclopedia of Dietary
Supplements. 2nd
ed. New York, NY: Informa Healthcare; 2010:226-234.
- Echinacea.
In: Blumenthal M, Goldberg A, Brinckmann J, eds. Herbal Medicine: Expanded
Commission E Monographs. Newton,
MA: Integrative Medicine Communications; 2000:88-102.
- Echinacea.
Natural Medicines Web site. Accessed at
naturalmedicines.therapeuticresearch.com on April 3, 2015.
[Database subscription].
- Gurley
BJ, Fifer EK, Gardner Z. Pharmacokinetic
herb-drug interactions (part 2): drug interactions involving popular
botanical dietary supplements and their clinical relevance. Planta Medica. 2012;78(13):1490-1514.
- Karsch-Volk
M, Barrett B, Kiefer D, et al. Echinacea for
preventing and treating the common cold. Cochrane Database of Systematic
Reviews. 2014;(2):CD000530.
Accessed at http://www.thecochranelibrary.com(link
is external) on
April 6, 2015.
- Karsch-Volk
M, Barrett B, Linde K. Echinacea for
preventing and treating the common cold. JAMA. 2015;313(6):618-619.
- Taylor
JA, Weber W, Standish L, et al. Efficacy
and safety of echinacea in treating upper respiratory tract infections
in children: a randomized controlled trial. JAMA. 2003;290(21):2824-2830.
-NIH