Green Tea
Background
Green, black, and oolong teas all come from the same plant,
Camellia sinensis,
but are prepared using different methods. To produce green tea, fresh
leaves from the plant are lightly steamed.
Tea has been used for medicinal purposes in China and Japan for
thousands of years.
Current
uses of green tea as a beverage or dietary supplement include improving
mental alertness, relieving digestive symptoms and headaches, and
promoting weight loss. Green tea and its extracts, such as one of its
components, EGCG, have been studied for their possible protective
effects against heart disease and cancer.
Green tea is consumed
as a beverage. It is also sold in liquid extracts, capsules, and
tablets and is sometimes used in topical products (intended to be
applied to the skin).
How Much Do We Know?
Although
many studies have been done on green tea and its extracts, definite
conclusions cannot yet be reached on whether green tea is helpful for
most of the purposes for which it is used.
What Have We Learned?
There’s evidence that green tea enhances mental alertness, as would be
expected because of its caffeine content.
The
U.S. Food and Drug Administration has approved a specific green tea
extract ointment as a prescription drug for treating
genital warts.
Studies
of green tea and cancer in people have had inconsistent results. The
National Cancer Institute does not recommend for or against using green
tea to reduce the risk of any type of cancer.
Very few
long-term studies have investigated the effects of tea on heart disease
risk. However, the limited evidence currently available suggests that
both green and black tea might have beneficial effects on some heart
disease risk factors, including blood pressure and cholesterol.
Green
tea extracts haven’t been shown to produce a meaningful weight loss in
overweight or obese adults. They also haven’t been shown to help people
maintain a weight loss.
The National Center for Complementary
and Integrative Health (NCCIH) is funding research on green tea and its
extracts, including studies of the effects of high doses of tea
components on the liver, whether substances in green tea can be helpful
for iron overload disease, and the safety of a component of green tea
in people who are HIV-positive.
What Do We Know About Safety?
Green tea, when consumed as a beverage, is believed to be safe when
used in moderate amounts.
Liver
problems have been reported in a small number of people who took
concentrated green tea extracts. Although the evidence that the green
tea products caused the liver problems is not conclusive, experts
suggest that concentrated green tea extracts be taken with food and
that people discontinue use and consult a health care provider if they
have a liver disorder or develop symptoms of liver trouble, such as
abdominal pain, dark urine, or jaundice.
Except for
decaffeinated green tea products, green tea and green tea extracts
contain substantial amounts of caffeine. Too much caffeine can make
people feel jittery and shaky; interfere with sleep; and
cause headaches.
Green tea has been shown to reduce blood
levels (and therefore the effectiveness) of the drug nadolol, a
beta-blocker used for high blood pressure and heart problems. It may
also interact with other medicines.
Keep in Mind
Tell
all your health care providers about any complementary or integrative
health approaches you use. Give them a full picture of what you do to
manage your health. This will help ensure coordinated and
safe care.
Key References
- Boehm
K, Borrelli F, Ernst E, et al. Green tea (Camellia sinensis) for the
prevention of cancer. Cochrane Database of Systematic
Reviews. 2009;(3):CD005004
[edited 2010]. Accessed at http://www.thecochranelibrary.com(link
is external) on
April 16, 2015.
- Green
tea. Natural Medicines Web site. Accessed at
naturalmedicines.therapeuticresearch.com/ on April 16, 2015.
[Database subscription].
- Hartley
L, Flowers N, Holmes J, et al. Green and black tea for the primary
prevention of cardiovascular disease. Cochrane Database of Systematic
Reviews. 2013;(6):CD009934.
Accessed at http://www.thecochranelibrary.com(link
is external) on
April 16, 2015.
- Jurgens
TM, Whelan AM, Lillian L, et al. Green tea for weight loss and weight
maintenance in overweight or obese adults. Cochrane Database of Systematic
Reviews. 2012;(12):CD008650.
Accessed at http://www.thecochranelibrary.com(link
is external) on
April 16, 2015.
- Misaka
S, Yatabe J, Muller F, et al. Green
tea ingestion greatly reduces plasma concentrations of nadolol in
healthy subjects. Clinical Pharmacology and
Therapeutics. 2014;95(4):432-438.
- Mooiman
KD, Maas-Bakker RF, Hendrikx JJ, et al. The
effect of complementary and alternative medicines on CYP3A4-mediated
metabolism of three different substrates:
7-benzyloxy-4-trifluoromethyl-coumarin, midazolam and docetaxel. Journal of Pharmacy and
Pharmacology. 2014;66(6):865-874.
- National
Cancer Institute. Tea and Cancer Prevention.
Strengths and Limits of the Evidence. National
Cancer Institute Web site. Accessed at https://www.cancer.gov/cancertopics/causes-prevention/risk/diet/tea-fact-sheet on
April 16, 2015.
- Sang
S, Lambert JD, Ho C-T, et al. Green tea polyphenols. In: Coates PM,
Betz JM, Blackman MR, et al., eds. Encyclopedia of Dietary
Supplements. 2nd
ed. New York, NY: Informa Healthcare; 2010:402-410.
- Sarma
DN, Barrett ML, Chavez ML, et al. Safety
of green tea extracts: a systematic review by the US Pharmacopeia. Drug Safety. 2008;31(6):469-484.
- Werba
JP, Misaka S, Giroli MG, et al. Overview
of green tea interaction with cardiovascular drugs. Current Pharmaceutical Design. 2015;21(9):1213-1219.
-NIH