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Kava



Background

Kava is native to the islands of the South Pacific and is a member of the pepper family.

Pacific islanders have used kava in ceremonies to bring about a state of relaxation.

Today, people use kava as a dietary supplement for anxiety.

The root and underground stem (fresh or dried) are used to prepare drinks; they are also made into extracts, capsules, and tablets.

How Much Do We Know?

There is a fair amount of clinical research on kava.

What Have We Learned?

Kava supplements may have a small effect on reducing anxiety, but they have been linked to a risk of severe liver disease.

Differences in dosages used, preparation methods, and study designs have resulted in mixed conclusions about kava’s usefulness.

What Do We Know About Safety?

In March 2002, the U.S. Food and Drug Administration warned health care providers and the public about the risk of liver damage associated with kava.

Combining kava with alcohol may increase the risk of liver damage.

Long-term use of high doses of kava has been associated with dry, scaly skin or yellowing of the skin.

Heavy consumption of kava has been associated with heart problems and eye irritation.

Keep in Mind

Tell all your health care providers about any complementary or integrative health approaches you use. Give them a full picture of what you do to manage your health. This will help ensure coordinated and safe care.

Key References

  • Chiappedi M, de Vincenzi S, Bejor M. Nutraceuticals in psychiatric practice.Recent Patents on CNS Drug Discovery. 2012;7(2):163-172.
  • Feucht C, Patel DR. Herbal medicines in pediatric neuropsychiatry. Pediatric Clinics of North America. 2011;58(1):33-54.
  • Kava. Natural Medicines Database Web site. Accessed at naturalmedicines.therapeuticresearch.com on April 8, 2015. [Database subscription].
  • Pittler MH, Ernst E. Kava extract versus placebo for treating anxiety. Cochrane Database of Systematic Reviews. 2003;(1):CD003383 [edited 2010]. Accessed at http://www.thecochranelibrary.com(link is external) on April 30, 2015.
  • U.S. Food and Drug Administration. Consumer Advisory: Kava-Containing Dietary Supplements May Be Associated With Severe Liver Injury. U.S. Food and Drug Administration Web site. Accessed at http://www.fda.gov/Food/ResourcesForYou/Consumers/ucm085482.htm on April 30, 2015.

-NIH



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