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ALOXI- palonosetron hydrochloride injection

Patient Information

See FDA-approved patient labelling (Patient Information).

Instructions for Patients

Patients should be advised to report to their physician all of their medical conditions, including any pain, redness, or swelling in and around the infusion site[see Adverse Reactions (6.3)].

Advise patients of the possibility of serotonin syndrome, especially with concomitant use of ALOXI and another serotonergic agent such as medications to treat depression and migraines. Advise patients to seek immediate medical attention if the following symptoms occur: changes in mental status, autonomic instability, neuromuscular symptoms with or whithout gastrointestinal symptoms [see Warnings and Precautions (5.2)].

Patients should be instructed to read the Patient Information.

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