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CINVANTI- aprepitant injection, emulsion


  1. Patient Information
  2. Do Not Receive Cinvanti If You:
  3. What Are The Possible Side Effects Of Cinvanti?cinvanti May Cause Serious Side Effects, Including:
  4. The Most Common Side Effects Of Cinvanti Include: Headache, Tiredness And Belching Or Burping (eructation).infusion-site Side Effects With Cinvanti May Include:
  5. What Are The Ingredients In Cinvanti?

Patient Information 

Advise the patient to read the FDA-approved patient labeling (Patient Information).

Hypersensitivity

Advise patients that hypersensitivity reactions, including anaphylaxis, have been reported[
CINVANTI is a prescription medicine used with other medicines that treat nausea and vomiting in adults to prevent nausea and vomiting caused by certain anti-cancer (chemotherapy) medicines.

  • CINVANTI is not used to treat nausea and vomiting that you already have.
  • It is not known if CINVANTI is safe and effective in children.

Do Not Receive Cinvanti If You: 


  • are allergic to aprepitant, or any of the ingredients in CINVANTI.
    • CINVANTI is given on Day 1. It will be given to you by intravenous (IV) injection or infusion in your vein about 30 minutes before you start your chemotherapy treatment.
    • If you take the blood thinner medicine warfarin sodium (COUMADIN, JANTOVEN), your healthcare provider may do blood tests after you receive CINVANTI to check your blood clotting.

What Are The Possible Side Effects Of Cinvanti?cinvanti May Cause Serious Side Effects, Including: 

  • Serious allergic reactions.Serious allergic reactions can happen during your CINVANTI infusion. Tell your healthcare provider or nurse right away if you get any of these symptoms during or soon after your infusion:
    • trouble breathing or swallowing, shortness of breath or wheezing
    • swelling of your eyes, face, tongue, or throat
    • flushing or redness of your face or skin
    • hives, rash, itching
    • dizziness, a rapid or weak heartbeat, or you feel faint

The Most Common Side Effects Of Cinvanti Include: Headache, Tiredness And Belching Or Burping (eructation).infusion-site Side Effects With Cinvanti May Include: 

pain, hardening, redness or itching at the site of infusion. Swelling (inflammation) of a vein caused by a blood clot can also happen at the infusion site. Tell your healthcare provider if you get any infusion-site side effects.
Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all of the possible side effects of CINVANTI. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.General information about the safe and effective use of CINVANTI.
Medicines are sometimes prescribed for purposes other than those listed in a Patient Information leaflet. You can ask your healthcare provider or pharmacist for information about CINVANTI that is written for health professionals.

What Are The Ingredients In Cinvanti? 


Active ingredient: aprepitant
Inactive ingredients: egg lecithin, ethanol, sodium oleate, soybean oil, sucrose, and water for injection.Manufactured for: Heron Therapeutics, Inc., San Diego, CA, 92121, USA
Copyright 2019 HERON THERAPEUTICS, San Diego, CA, 92121, USA. All rights reserved
For more information about CINVANTI call 1-844-437-6611 or go to www.CINVANTI.com.

This Patient Information has been approved by the U.S. Food and Drug Administration Approved: February 2019



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