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DESVENLAFAXINE SUCCINATE tablet, extended release


  1. Patient Information
  2. Desvenlafaxine Can Cause Serious Side Effects, Including:
  3. Depression Or Other Serious Mental Illnesses Are The Most Important Causes Of Suicidal Thoughts Or Actions.how Can I Watch For And Try To Prevent Suicidal Thoughts And Actions?
  4. Call Your Healthcare Provider Right Away If You Have Any Of The Following Symptoms, Especially If They Are New, Worse, Or Worry You:
  5. What Is Desvenlafaxine?
  6. What Are The Possible Side Effects Of Desvenlafaxine?
  7. What Are The Ingredients In Desvenlafaxine?active Ingredient:
  8. 25 Mg Tablet:
  9. 50 Mg Tablet:
  10. 100 Mg Tablet:

Patient Information 

Advise the patient to read the FDA-approved patient labeling (Medication Guide).

Suicidal Thoughts and Behaviors

Advise patients and caregivers to look for the emergence of suicidality, especially early during treatment and when the dose is adjusted up or down, and instruct them to report such symptoms to the healthcare provider[

Desvenlafaxine Can Cause Serious Side Effects, Including: 

  • Increased risk of suicidal thoughts or actions in some children and young adults within the first few months of treatment. Desvenlafaxine is not for use in children.

Depression Or Other Serious Mental Illnesses Are The Most Important Causes Of Suicidal Thoughts Or Actions.how Can I Watch For And Try To Prevent Suicidal Thoughts And Actions? 

  • Pay close attention to any changes, especially sudden changes, in mood, behaviors, thoughts, or feelings. This is very important when an antidepressant medicine is started or when the dose is changed.
  • Call the healthcare provider right away to report new or sudden changes in mood, behavior, thoughts, or feelings.
  • Keep all follow-up visits with the healthcare provider as scheduled. Call the healthcare provider between visits as needed, especially if you have concerns about symptoms.

Call Your Healthcare Provider Right Away If You Have Any Of The Following Symptoms, Especially If They Are New, Worse, Or Worry You: 

  • thoughts about suicide or dying
  • attempts to commit suicide
  • new or worse depression
  • new or worse anxiety
  • feeling very agitated or restless
  • panic attacks
  • trouble sleeping (insomnia)
  • new or worse irritability
  • acting aggressive, being angry, or violent
  • acting on dangerous impulses
  • an extreme increase in activity and talking (mania)
  • other unusual changes in behavior or mood

What Is Desvenlafaxine? 

  • Desvenlafaxine is a prescription medicine used to treat adults with a certain type of depression called major depressive disorder (MDD). Desvenlafaxine belongs to a class of medicines known as serotonin and norepinephrine reuptake inhibitors (SNRIs).
Do not take desvenlafaxine if you:
  • are allergic to desvenlafaxine, venlafaxine hydrochloride, or any of the ingredients in desvenlafaxine.
    • Take desvenlafaxine exactly as your healthcare provider tells you to.
    • Take desvenlafaxine 1 time a day at about the same time each day.
    • Desvenlafaxine may be taken either with or without food.
    • Swallow desvenlafaxine tablets whole, with fluid. Do not divide, crush, chew, or dissolve desvenlafaxine tablets.
    • When you take desvenlafaxine, you may
      • Do not drive a car or operate heavy machinery until you know how desvenlafaxine affects you.
      • You should not drink alcohol while taking desvenlafaxine.

What Are The Possible Side Effects Of Desvenlafaxine? 

Desvenlafaxine can cause serious side effects, including:
    • Store desvenlafaxine at room temperature between 68 F to 77 F (20 C to 25 C).
    • Keep desvenlafaxine and all medicines out of the reach of children.
    General Information about the safe and effective use of desvenlafaxine
    Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide. Do not take desvenlafaxine for a condition for which it was not prescribed. Do not give desvenlafaxine to other people, even if they have the same symptoms that you have. It may harm them. You can ask your pharmacist or healthcare provider for information about desvenlafaxine that is written for healthcare professionals.

What Are The Ingredients In Desvenlafaxine?active Ingredient: 

desvenlafaxine

25 Mg Tablet: 

hypromellose, microcrystalline cellulose, talc, magnesium stearate, a film coating which consists of polyvinyl alcohol, polyethylene glycol, talc, titanium dioxide, and iron oxides.

50 Mg Tablet: 

hypromellose, microcrystalline cellulose, talc, magnesium stearate and film coating, which consists of polyvinyl alcohol, polyethylene glycol, talc, titanium dioxide, and iron oxides.

100 Mg Tablet: 

hypromellose, microcrystalline cellulose, talc, magnesium stearate, a film coating which consists of polyvinyl alcohol, polyethylene glycol, talc, titanium dioxide, iron oxide and FD&C yellow #6.

This product's label may have been updated. For current full prescribing information, please visitwww.greenstonellc.com.

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LAB-0781-4.0
For more information, go to www.greenstonellc.com or call 1-800-438-1985.



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