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EMEND- aprepitant capsuleEMEND- aprepitant kitEMEND- aprepitant powder, for suspension


  1. Patient Information
  2. Do Not Take Emend If You:
  3. Before You Take Emend, Tell Your Healthcare Provider If You:
  4. How Should I Take Emend?
  5. In Adults, There Are 2 Ways Your Healthcare Provider May Prescribe Emend For You:
  6. Capsules Of Emend By Mouth For All 3 Doses:
  7. Day 1 (day Of Chemotherapy):
  8. Day 2 And Day 3:
  9. Oral Suspension Of Emend By Mouth For All 3 Doses, For Adults Who Are Not Able To Swallow Capsules:
  10. How Should I Store Emend?
  11. Active Ingredient:
  12. Inactive Ingredients:

Patient Information 

Advise the patient to read the FDA-approved patient labeling (Patient Information).

Hypersensitivity Reactions

Advise patients that hypersensitivity reactions, including anaphylaxis, have been reported in patients taking EMEND. Advise patients to stop taking EMEND and EMEND for oral suspensionis a prescription medicine used:

  • with other medicines that treat nausea and vomiting in patients 6 months of age and older to prevent nausea and vomiting caused by certain anti-cancer (chemotherapy) medicines
EMEND capsulesis a prescription medicine used:
  • with other medicines that treat nausea and vomiting in patients 12 years of age and older to prevent nausea and vomiting caused by certain anti-cancer (chemotherapy) medicines
EMEND is not used to treat nausea and vomiting that you already have.EMEND should not be used continuously for a long time (chronic use).

Do Not Take Emend If You: 

  • are allergic to aprepitant or any of the ingredients in EMEND.

Before You Take Emend, Tell Your Healthcare Provider If You: 

  • have liver problems
  • are pregnant or plan to become pregnant. It is not known if EMEND can harm your unborn baby.
    • Women who use birth control medicines containing hormones to prevent pregnancy (birth control pills, skin patches, implants, and certain IUDs) should also use a back-up method of birth control that does not contain hormones, such as condoms and spermicides, during treatment with EMEND and for 1 month after your last dose of EMEND.
  • are breastfeeding or plan to breastfeed. It is not known if EMEND passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby if you take EMEND.
Tell your healthcare provider about all the medicines you take,including prescription and over-the-counter medicines, vitamins, and herbal supplements.EMEND may affect the way other medicines work, and other medicines may affect how EMEND works causing serious side effects.Know the medicines you take. Keep a list of them to show your healthcare provider or pharmacist when you get a new medicine.

How Should I Take Emend? 

  • Take EMEND exactly as prescribed.
  • Swallow EMEND capsules whole.
  • EMEND may be taken with or without food.
  • If you take too much EMEND, call your healthcare provider, or go to the nearest hospital emergency room.
  • EMEND is taken as 3 doses over 3 days - starting on the day you have chemotherapy, and for the following 2 days.

In Adults, There Are 2 Ways Your Healthcare Provider May Prescribe Emend For You: 

1.

Capsules Of Emend By Mouth For All 3 Doses: 

  • You should get a package that has 3 capsules of EMEND.

Day 1 (day Of Chemotherapy): 

Take one 125 mg capsule of EMEND (white and pink) by mouth 1 hour before you start your chemotherapy treatment.

Day 2 And Day 3: 

Take one 80 mg capsule of EMEND (white) by mouth 1 hour before you start your chemotherapy treatment. If no chemotherapy treatment is given on Days 2 and 3, EMEND should be taken in the morning.
2.

Oral Suspension Of Emend By Mouth For All 3 Doses, For Adults Who Are Not Able To Swallow Capsules: 

  • For each dose of EMEND for oral suspension, you will get a pre-filled oral dosing dispenser that contains your prescribed dose.
    • In adults taking EMEND, the most common side effects include tiredness, diarrhea, weakness, indigestion, stomach (abdominal) pain, hiccups, decrease in white blood cell count, dehydration, and changes in liver function tests.
    • In children 6 months to 17 years of age, the most common side effects include decrease in white blood cell count, headache, diarrhea, decreased appetite, cough, tiredness, decrease in red blood cell count, dizziness, and hiccups.
    Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all of the possible side effects of EMEND. For more information ask your healthcare provider or pharmacist.Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

How Should I Store Emend? 

EMEND capsules
  • Store EMEND capsules at room temperature, between 68 F to 77 F (20 C to 25 C).
EMEND for oral suspension
  • Store EMEND for oral suspension in the refrigerator, between 36 F to 46 F (2 C to 8 C).
  • Use EMEND for oral suspension within 2 days of getting the medicine from your healthcare provider.
  • When ready to use, EMEND for oral suspension can be kept at room temperature, between 68 F to 77 F (20 C to 25 C) for up to 3 hours.
Keep EMEND and all medicines out of the reach of children.General information about the safe and effective use of EMENDMedicines are sometimes prescribed for purposes other than those listed in a Patient Information leaflet. Do not use EMEND for a condition for which it was not prescribed. Do not give EMEND to other people, even if they have the same symptoms you have. It may harm them. You can ask your healthcare provider or pharmacist for information about EMEND that is written for health professionals. For more information about EMEND call 1-800-622-4477 or go to www.emend.com.

Active Ingredient: 

aprepitant

Inactive Ingredients: 

sucrose, lactose, hydroxypropyl cellulose, sodium lauryl sulfate, red iron oxide, and sodium stearyl fumarate.Distributed by: Merck Sharp & Dohme Corp., a subsidiary ofMERCK & CO., INC.,Whitehouse Station, NJ 08889, USA
For patent information: www.merck.com/product/patent/home.html
The brands listed in the above sections "Who should not take EMEND?" and "How should I take EMEND?" are the registered trademarks of their respective owners and are not trademarks of Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc.
Copyright 2003-2019 Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc.
All rights reserved.
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