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EXTAVIA- interferon beta-1b kit


  1. Patient Information
  2. Tell Patients Not To Re-use Needles Or Syringes, And Instruct Patients On Safe Disposal Procedures. Advise Patients Of The Importance Of Rotating Areas Of Injection With Each Dose, To Minimize The Likelihood Of Severe Injection-site Reactions, Including Necrosis Or Localized Infection(extavia Can Cause Serious Side Effects, Including:
  3. What Is Extavia?
  4. Extavia May Cause Serious Side Effects. Call Your Healthcare Provider Right Away If You Have Any Of The Serious Side Effects Of Extavia, Including:
  5. Active Ingredient:
  6. Inactive Ingredients:

Patient Information 

Advise the patient to read the FDA-approved patient labeling (Medication Guide and Instructions for Use).

Instruction on Self-injection Technique and Procedures

Provide appropriate instruction for reconstitution of EXTAVIA and methods of self-injection, including careful review of the EXTAVIA Medication Guide. Instruct patients in the use of aseptic technique when administering EXTAVIA.

Tell Patients Not To Re-use Needles Or Syringes, And Instruct Patients On Safe Disposal Procedures. Advise Patients Of The Importance Of Rotating Areas Of Injection With Each Dose, To Minimize The Likelihood Of Severe Injection-site Reactions, Including Necrosis Or Localized Infection(extavia Can Cause Serious Side Effects, Including: 

liver problems including liver failure.Symptoms of liver problems may include:

yellowing of your eyes
flu-like symptoms
itchy skin
nausea or vomiting
feeling very tired
bruising easily or bleeding problemsYour healthcare provider will do blood tests to check for these problems while you take EXTAVIA.

serious allergic reactions.Serious allergic reactions can happen quickly and may happen after your first dose of EXTAVIA or after you have taken EXTAVIA many times. Symptoms may include: difficulty breathing or swallowing or swelling of the mouth or tongue, rash, itching, or skin bumps
depression or suicidal thoughts.Call your healthcare provider right away if you have any of the following symptoms, especially if they are new, worse, or worry you:

thoughts about suicide or dying
trouble sleeping (insomnia)
hallucinationsnew or worse depression
acting aggressive, being angry, or violent
other unusual changes in behavior or moodnew or worse anxiety
acting on dangerous impulses

What Is Extavia? 


EXTAVIA is a prescription medicine used to treat relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults. EXTAVIA is similar to certain interferon proteins that are produced in the body. It is not known if EXTAVIA is safe and effective in children.Who should not take EXTAVIA?
Do not take EXTAVIA if you
are allergic to interferon beta-1b, to another interferon beta, to human albumin, or mannitol.

Extavia May Cause Serious Side Effects. Call Your Healthcare Provider Right Away If You Have Any Of The Serious Side Effects Of Extavia, Including: 

    • Before mixing, store EXTAVIA at room temperature between 68 F to 77 F (20 C to 25 C).
    • Before mixing, EXTAVIA may be stored for up to 3 months between 59 F to 86 F (15 C to 30 C).
    • After mixing, you can refrigerate EXTAVIA for up to 3 hours before using. Your EXTAVIA must be used within 3 hours of mixing even if refrigerated.
    • Do not freeze.

    Keep EXTAVIA and all medicines out of the reach of children.

    General information about the safe and effective use of EXTAVIA.
    Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide. Do not use EXTAVIA for a condition for which it was not prescribed. Do not give EXTAVIA to other people, even if they have the same symptoms that you have. It may harm them.
    This Medication Guide summarizes the most important information about EXTAVIA. If you would like more information, talk with your healthcare provider. You can ask your pharmacist or healthcare provider for information about EXTAVIA that is written for health professionals.
    For more information, go to www.EXTAVIA.com or call the EXTAVIA toll-free medical information line at 1-888-669-6682.

Active Ingredient: 

interferon beta-1b

Inactive Ingredients: 

albumin (human), mannitol
Diluent contains sodium chloride solution.

Manufactured by:
Novartis Pharmaceuticals Corporation
East Hanover, New Jersey 07936
U.S. License No. 1244

T2019-95



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